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Arachnoiditis is a pain disorder caused by the inflammation
of the arachnoid, one of the membranes that surround and protect
the nerves of the spinal cord. It is characterized by severe
stinging, "burning pain," and neurological problems.
Causes of Arachnoiditis
Inflammation of the arachnoid can lead to the formation of
scar tissue and can cause the spinal nerves to stick together
and malfunction. The arachnoid can become inflamed because
of an irritation from one of the following sources: direct
injury, chemicals previously used in myelograms, infection,
chronic spinal nerve compression and complications from spinal
surgery or invasive procedures.
Symptoms of Arachnoiditis
Arachnoiditis has no consistent pattern of symptoms, but in
many people it affects the nerves connecting to the lower
back and legs. The most common symptom is pain; but, arachnoiditis
can also cause other symptoms. These include the following:
tingling, numbness, weakness in the legs. Abnormal sensations
like crawling insects, electric shocks, spasms, twitching,
as well as bowel, bladder or sexual dysfunction may also occur.
The condition is difficulty to diagnosis, but tests such as
a CT scan (computerized axial tomography) or MRI (magnetic
resonance imaging) are helpful. A test called an electromyogram
(EMG) can assess the severity of the ongoing damage to affected
nerve roots by using electrical impulses to check nerve function.
Treatment of Arachnoiditis
There is no cure for arachnoiditis. Treatment options for
arachnoiditis are similar to those for other chronic pain
conditions. Most treatments focus on relieving pain and improving
symptoms that impair daily activities. Often, health care
professionals recommend a program of pain management, physiotherapy,
exercise, and psychotherapy. Surgery for arachnoiditis is
controversial because outcomes can be poor and provide only
short-term relief. Clinical trials of steroid injections and
electrical stimulation are needed to determine whether those
treatments are effective.
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Complex Regional Pain Syndrome (CRPS) is a chronic disease
characterized by severe pain, swelling and changes in the
skin. CRPS into two types based on the presence of nerve lesion
following the injury.
Type I, also known as Reflex Sympathetic Dystrophy (RSD),
Sudeck's atrophy, Reflex Neurovascular Dystrophy (RND) or
Algoneurodystrophy, does not have demonstrable nerve lesions.
Type II, also known as Causalgia, has evidence of obvious
nerve damage.
Causes of Complex Regional Pain Syndrome
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The cause of this syndrome is currently unknown. Precipitating
factors include illness, injury and surgery, although
there are documented cases that have no documentable
injury to the place originally affected by complex
regional pain syndrome. |
Symptoms of Complex
Regional Pain Syndrome
The symptoms of CRPS usually begin near the site of an injury,
either major or minor, and usually spread beyond the original
area. Symptoms may spread to involve the entire limb and,
rarely, the opposite limb. The most common symptom is burning
pain. The patient may also experience muscle spasms, local
swelling, increased sweating, softening of bones, joint tenderness
or stiffness, restricted or painful movement, and changes
in the nails and skin.
The pain of CRPS is continuous and may be heightened by emotional
stress. Moving or touching the limb is often intolerable.
Eventually the joints become stiff from disuse, and the skin,
muscles, and bone atrophy. The symptoms of CRPS vary in severity
and duration. There are three variants of CRPS, previously
thought of as stages. It is now believed that patients with
CRPS do not progress through these stages sequentially and/or
that these stages are not time-limited. Instead, patients
are likely to have one of the three following types of disease
progression:
- Type one is characterized by severe, burning pain at
the site of the injury. Muscle spasm, joint stiffness,
restricted mobility, rapid hair and nail growth, and vasospasm
(a constriction of the blood vessels) that affects color
and temperature of the skin can also occur.
- Type two is characterized by more intense pain. Swelling
spreads, hair growth diminishes, nails become cracked,
brittle, grooved, and spotty, osteoporosis becomes severe
and diffuse, joints thicken, and muscles atrophy.
- Type three is characterized by irreversible changes
in the skin and bones, while the pain becomes unyielding
and may involve the entire limb. There is marked muscle
atrophy, severely limited mobility of the affected area,
and flexor tendon contractions (contractions of the muscles
and tendons that flex the joints). Occasionally the limb
is displaced from its normal position, and marked bone
softening is more dispersed.
No specific test is available for CRPS, which is diagnosed
primarily through observation of the symptoms. However, thermography,
sweat testing, x-rays, electrodiagnostics, and sympathetic
blocks can be used to build up a picture of the disorder.
Diagnosis is complicated by the fact that some patients improve
without treatment. A delay in diagnosis and/or treatment for
this syndrome can result in severe physical and psychological
problems. Early recognition and prompt treatment provide the
greatest opportunity for recovery. It is not usual for the
course of this syndrome to change suddenly.
Treatment of Complex Regional Pain
Syndrome
The general strategy in CRPS treatment is often multi-disciplinary,
with the use of different types of medications combined with
distinct physical therapies. The goal of treatment is to manage
the symptoms and maintain or improve function of the affected
area. The quicker the diagnosis is made and the area is treated,
the more likely the problem is to go into remission.
Physicians use a variety of drugs to treat CRPS, including
antidepressants, anti-inflammatories such as corticosteroids
and COX-inhibitors such as piroxicam, vasodilators, GABA analogs
such gabapentin and pregabalin, and alpha- or beta-adrenergic-blocking
compounds.
Sympathetic blocks of the affected area can be helpful to
decrease symptoms and allow more effective rehabilitation.
These include lumbar sympathetic blocks, stellate ganglion
blocks, and are some cases, sympathetic radiofrequency sympathectomy.
Neurostimulation (spinal cord stimulators) may also be surgically
implanted to reduce the pain by directly stimulating the spinal
cord. These devices place electrodes either in the epidural
space (space above the spinal cord) or directly over nerves
located outside the central nervous system. Implantable drug
pumps may also be used to deliver pain medication directly
to the cerebrospinal fluid which allows powerful opioids to
be used in a much smaller dose than when taken orally.
Alternative treatments for complex regional pain syndrome
include accupuncture or Ketamine therapy. Ketamine is a potent
anesthetic, and is administered in different doses in an attempt
to “reboot” the abnormal brain activity. These
treatments are controversial, and some forms of Ketamine therapy
are not approved for use in the United States.
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Degeneration of the intervertebral disc, which is often called
"degenerative disc disease" (DDD) of the spine,
is a condition that can be painful and can greatly affect
the quality of one's life. While disc degeneration is
a normal part of aging and for most people is not a
problem, for certain individuals a degenerated disc
can cause severe constant chronic pain. |
Causes of Degenerative Disc Disease
Everyone experiences degeneration of the intervertebral discs
with age. Injuries, either large or small, are the most common
cause of disc degeneration. After injury, the discs in the
spine dehydrate, or dry out, and lose their ability to act
as shock absorbers between the vertebrae. There is minimal
blood supply to the discs so they are unable to heal or repair
themselves.
Symptoms of Degenerative Disc Disease
With symptomatic degenerative disc disease, chronic low back
pain sometimes radiates to the hips, or there is pain in the
buttocks or thighs while walking; sporadic tingling or weakness
through the knees may also be evident. Similar pain may be
felt or may increase while sitting, bending, lifting, and
twisting.
Treatment of Degenerative Disc Disease
Conservative treatment is the first choice for degenerative
disc disease. One or a combination of treatments such as physical
therapy, home exercise, osteopathic manipulation, anti-inflammatory
medications such as nonsteroidal anti-inflammatory drugs and
spinal injections often provide adequate relief of these troubling
symptoms. By completing diagnostic median branch blocks, doctors
can evaluate how much of the discomfort is coming from the
facet joints. If this is found to be one of the sources of
pain, the nerves sending pain signals from those joints can
be treated with radiofrequency rhizotomy.
Surgery is rarely considered unless the degenerative changes
in the spine cause a progressive neurological problem and
the symptoms to not respond to conservative care.
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Failed Back Syndrome (FBS) or Post-laminectomy Syndrome is
a condition characterized by persistent pain following back
surgeries.
Failed back syndrome (FBS), more commonly referred to as "failed
back surgery syndrome" (FBSS), refers to chronic back
and/or leg pain that occurs after back (spinal) surgery. Multiple
things can contribute to FBS. These include residual or recurrent
disc herniation, continued post-operative pressure on a spinal
nerve, joint hypermobility with instability, scar tissue (fibrosis),
depression, anxiety, sleeplessness and loss of spinal muscle
tone. Patients may be more at risk for the problem because
of diabetes, autoimmune disease and peripheral blood vessels
(vascular) disease. Smoking is a risk for poor recovery from
such an operation.
Causes of the Failed Back Syndrome
Surgeons will argue that the cause of FBSS "can be poor
patient selection, incorrect diagnosis, suboptimal selection
of surgery, poor technique ...and/or recurrent pathology",
as well as including "failure to achieve surgical goals".
Unfortunately the causes of continued pain are difficult to
identify and pain can become chronic. Repeated surgical intervention
is not usually helpful. For those contemplating more surgery
additional complications must be considered. Complications
of spinal fusion surgery may include instrument failure, bone-donor
site infection or chronic pain; neural injuries, pulmonary
embolus, infections, vascular complications (rare but potentially
very serious) and failure to achieve a solid fusion.
Symptoms of Failed Back Syndrome
Common symptoms associated with FBS include generalized, dull
and aching pain involving the back and/or legs. Abnormal sensations
may include sharp, pricking, and stabbing pain in the legs.
The term “post-laminectomy syndrome” is used by
some doctors to indicate the same condition as failed back
syndrome.
Treatment of Failed Back Syndrome
The goal of the treatment for FBS is based on helping the
patient control the symptoms and improve their quality of
life. Gradually increasing exercise and changing the lifestyle
to avoid things that increase the pain are very important.
Treatment can include medications for pain and inflammation.
Medications to change the way pain signals are sent in the
body, such as gabapentin (Neurontin), pregabilin (Lyrica)
and amitriptyline (Elavil) may improve the pain. Medications
for depression may also be helpful. Interventional (injection)
treatments to treat some of the sources of pain include diagnostic
blocks to evaluate the pain sources. Pain coming from the
facet joints may improve with radiofrequency rhizotomy. Epidural
steroid injections may also help improve pain, particularly
if it goes into the legs.
In addition, more invasive modalities, such as spinal cord
stimulation, may offer relief for certain patients with FBSS,
but these modalities, although often referred to as “minimally
invasive", require additional surgery, and have complications
of their own.
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A herniated disc is a disc that pushes into the spinal canal.
It may also be called a ruptured disc or slipped disc. As
a disc degenerates (breaks down with time), it can herniate
(the inner core pushes out) into the spinal canal. This occurs
when a tear in the outer, fibrous ring (annulus fibrosus)
of an intervertebral disc allows the soft, central portion
(nucleus pulposus) to bulge out. This tear in the disc may
result in the release of inflammatory chemical chemicals which
may directly cause severe pain, even in the nerves are not
directly compressed. This is called “chemical radiculitis”.
Causes of a Herniated Disc
The discs in your spine act like cushions, or shock absorbers.
With age, the discs start to dry out and become flatter. If
a disc becomes too weak, the outer part (annulus) may tear.
The inside (nucleus pulposus) part of the disc pushes through
the tear and can press on the nerves beside it. Herniated
discs most frequently occur in the lumbar (lower back) area,
but can also occur in the cervical (neck) and thoracic (mid-back)
spine.
Symptoms of a Herniated Disc
Symptoms of a herniated disc vary from person to person. Pain
usually occurs at the level of the herniated disc, but can
also be referred to other areas. If the herniated disc puts
pressure on one of the nerves in the spine, it may cause pain
to radiate to the legs (from the back) or the arms (from the
neck). When the disc herniates, it can also release chemicals
that can be very irritating to the surrounding tissues and
cause pain to radiate into the arms or legs. This is called
“chemical radiculitis”. Pain from lumbar herniated
discs commonly spreads into the buttock, down the thigh and
into the calf. This is commonly referred to as sciatica.
Other symptoms can include weakness, numbness, tingling, loss
of reflexes or muscle tone, foot drop, and loss of bowel and
bladder control. Pain usually worsens with activity, coughing,
sitting, bending forward and straining to have a bowel movement.
Treatment of a Herniated Disc
Treatment of a herniated disc usually begins with a period
of conservative treatment that may include medications, physical
therapy, home exercise and lifestyle modification. Patients
who do not improve with these conservative measures may respond
to epidural steroid or nerve root injections. In certain cases,
patients respond to disc decompression with devices such as
the DRX 9000. IDET can be helpful for selected patients. Patients
with herniated discs may also have facet related pain, which
responds to diagnostic blocks and radiofrequency.
Patients with severe symptoms that do not respond to other
treatment, or those that have symptoms that show nerve damage
is becoming progressively worse (i.e. loss of bowel or bladder
control, muscle wasting, progressive weakness) may be candidates
for surgery. Surgical procedures include laminectomy, discectomy
or fusion. Unfortunately, surgery is not recommended or effective
for all patients, and carries its own risks.
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Spinal Stenosis is the narrowing of the spinal canal by a
piece of bone or disc material.
This narrowing can put pressure on the spinal cord and/or
nerves. This can cause weakness or numbness in your arms or
legs. Spinal stenosis can occur in a variety of ways in the
spine. Most cases of spinal stenosis occur in the lower back
(lumbar spine) and will affect the nerves that run along the
back of the leg and cause pain or abnormal sensations.
Causes of Spinal Stenosis
Age related changes in the spine are the most common cause
of spinal stenosis. Over time, ligaments (strong tissues that
connect bones) get thicker. The disks between the vertebrae
(bones of the spine) may begin to break down, putting pressure
on other parts of the spine. The facet joints (small joints
between each vertebra) become thicker and decrease the space
around the nerves or spinal canal.
Spinal stenosis can also be found in younger people whose
spinal canal was smaller than usual, or who had deformed vertebrae
at birth. Spondylolisthesis (a slip of one vertebrae on another),
tumors of the spine and diffuse idiopathic skeletal hyperostosis
(DISH) can all also narrow the spinal canal and cause spinal
stenosis.
Symptoms of Spinal Stenosis
Spinal stenosis may result in low back pain or neck pain.
The pain may also occur in the arms or legs. It can cause
the weakness, numbness, decreased muscle size, loss of reflexes
in the arms or legs. Some people will notice a heavy, tired
feeling in the legs and symptoms can get severe enough to
make standing and walking difficult. Many patients notice
their pain improves with rest, sitting, or leaning forward
on things such as a shopping cart.
Treatment of Spinal Stenosis
Spinal stenosis treatment includes weight loss, and lifestyle
and activity changes. Epidural steroid injections may also
help relieve the symptoms. Lumbar facet blocks and radiofrequency
rhizotomy may help improve the back pain and some leg symptoms.
If the symptoms are severe enough to cause a progressive neurological
problem, a laminectomy or foraminotomy may be indicated to
take pressure off the spinal nerve.
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